This quick-reference table summarizes age-stratified Anti-Müllerian Hormone (AMH) and Antral Follicle Count (AFC) norms for ovarian reserve assessment. Use alongside patient age, FSH, and clinical history—AMH/AFC predict response to stimulation but not live birth rates.
AMH by Age (pmol/L and ng/mL)
| Age Range | Normal (50th %) | Good Reserve (>75th %) | Low (<25th %) | Clinical Notes |
|---|---|---|---|---|
| <25 | 28–42 pmol/L (1.8–2.8 ng/mL) |
>45 pmol/L (>3.0 ng/mL) |
<21 pmol/L (<1.4 ng/mL) |
Peak fertility window |
| 25–29 | 25–38 pmol/L (1.7–2.6 ng/mL) |
>40 pmol/L (>2.7 ng/mL) |
<18 pmol/L (<1.2 ng/mL) |
Expected decline begins |
| 30–34 | 20–32 pmol/L (1.4–2.2 ng/mL) |
>35 pmol/L (>2.4 ng/mL) |
<14 pmol/L (<1.0 ng/mL) |
Discuss egg freezing |
| 35–37 | 15–25 pmol/L (1.0–1.7 ng/mL) |
>28 pmol/L (>1.9 ng/mL) |
<10 pmol/L (<0.7 ng/mL) |
Sharp AMH drop post-36 |
| 38–40 | 9–18 pmol/L (0.6–1.2 ng/mL) |
>20 pmol/L (>1.4 ng/mL) |
<6 pmol/L (<0.4 ng/mL) |
Poor response likely |
| >40 | 4–12 pmol/L (0.3–0.8 ng/mL) |
>15 pmol/L (>1.0 ng/mL) |
<3 pmol/L (<0.2 ng/mL) |
Consider donor eggs |
Conversion: ng/mL × 7.14 = pmol/L
AFC by Age (Antral Follicle Count)
| Age Range | Normal (Mean) | Good (>75th %) | Low (<25th %) | IVF Stimulation Expectation |
|---|---|---|---|---|
| <30 | 18–25 follicles | ≥26 | ≤12 | 12–18 eggs expected |
| 30–34 | 15–22 | ≥23 | ≤10 | 8–14 eggs expected |
| 35–37 | 12–18 | ≥20 | ≤8 | 6–10 eggs expected |
| 38–40 | 8–14 | ≥16 | ≤5 | 3–7 eggs expected |
| >40 | 5–10 | ≥12 | ≤3 | ≤4 eggs expected |
How to count: 2-10 mm follicles, both ovaries, transvaginal ultrasound day 2-4. Strong correlation with AMH.
Updated Jan 2026.
Questions? Contact Dr. Shaw at Mint Reproductive Health, Vancouver.
References
Age-stratified anti-Müllerian hormone (AMH) nomogram. Frontiers in Endocrinology. 2025. https://www.frontiersin.org/journals/endocrinology/articles/10.3389/fendo.2025.1612194/full [frontiersin]
The Correlations of Anti-Mullerian Hormone, Follicle Stimulating Hormone, and Antral Follicle Count. PMC. 2015. https://pmc.ncbi.nlm.nih.gov/articles/PMC4355926/ [pmc.ncbi.nlm.nih]
Finding the Best IVF Protocol for Low AMH. Liv Hospital. 2025. https://int.livhospital.com/best-ivf-protocol-for-low-amh/ [int.livhospital]
Anti‐Müllerian hormone for screening, diagnosis, evaluation. J Obstet Gynaecol Res. 2023. https://obgyn.onlinelibrary.wiley.com/doi/10.1111/jog.15818 [obgyn.onlinelibrary.wiley]
